A newly issued 2016 QIO Program Progress Report from the U.S. Centers for Medicare & Medicaid Services (CMS) highlights the impact the regional Quality Innovation Network-Quality Improvement Organizations (QIN-QIOs) are having working with hospitals, nursing homes, home health agencies, physicians and other providers to meet or exceed specific government-issued quality improvement targets. Formerly state-based, these 14 multi-state organizations are currently finishing the third year of five year contracts that will conclude in 2018. IPRO leads the Atlantic Quality Innovation Network (AQIN), the QIN-QIO for New York, South Carolina and the District of Columbia. The services QIN-QIOs offer include technical assistance, education and outreach, data feedback and analysis, and provider-focused Learning and Action Networks (LANs). In some cases the QIOs offer support directly to beneficiaries-most notably in the area of diabetes self-management. The CMS report finds that QIN-QIOs are having their highest-level of impact in care coordination, diabetes care and nursing home care. Care coordination takes a community-based approach to examining indigenous factors affecting preventable and costly re-hospitalizations of Medicare beneficiaries. QIOs work with local providers to improve communications among hospitals, home health agencies, nursing homes primary care physicians and families, focusing on enhanced discharge planning, medication reconciliation and other issues that can reduce re-hospitalizations. According the CMS, QIOs engaged more than 350 communities across the U.S. in 2016, affecting as many as 23 million beneficiaries, with as many as 24,350 hospital readmissions avoided. In terms of diabetes care, QIOs engage in direct classroom-style teaching of self-management techniques to Medicare beneficiaries, with an emphasis on reaching inner city African-American and Latino seniors. Beneficiaries who reside in isolated rural communities are also targeted for diabetes self-management education (DSME), using evidence-based curricula that emphasize healthy eating and improved life-style choices. CMS finds that for 2016, QIOs trained more than 27,850 beneficiaries in DSME and taught DSME ”train-the-trainer” techniques to more than 3,300 diabetes educators. Classes were taught in ten different languages including Russian, Vietnamese, Swahili and Tagalog. In addition to enhancements in community-based care coordination and diabetes education, CMS credits QIOs with significant impact in recruiting nursing homes into local quality improvement activities. The agency finds that fully 74% of all skilled nursing facilities in the U.S. (11,450) now participate in QIO-convened quality improvement activities, accounting for a remarkable 21% reduction in homes’ use of antipsychotic medication nationwide. The Progress Report is available at http://qioprogram.org.